Santiago del Estero is an Argentine city, capital of the province of Santiago del Estero and head of the Capital department. It is the oldest city in the country that still stands. It is located on the banks of the Dulce River, and extends over an area of approximately 4002 hectares, officially divided into 62 neighborhoods.
According to the 2010 National Census, it had a population of 252 192 inhabitants. Next to the city of La Banda and the town of El Zanjón, it forms the urban agglomeration called Santiago del Estero-La Banda, the most populated urban center of the province and twelfth in the country, with 360 923 inhabitants.